Electrochemical Synthesis of 5-Aminosalicylic Acid from 5- Nitrosalicylic Acid in Alkaline Media

Document Type : Research Paper




5-Aminosalicylic acid (5-ASA) is currently prepared by electrochemical reduction of 5-nitrosalicylic acid (5-
NSA) in acidic media. In this work, electrolytic reduction of 5-NSA in alkaline media is presented. Reaction
conditions and parameters such as anode and cathode electrodes, electrolyte type, reaction time, temperature,
current, and the pH for isolation of product are investigated. The yield of the reaction was 90.9%, and the
melting point was 280 ° C with decomposition. The UV-Vis and FT-IR spectra of the product was in good
agreement with the standard material. The elemental analysis of the product was almost the same as the